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Hamilton Medical 哈美顿医疗公司标志 Hamilton Logo
 耗材

雾化。 高性能喷雾药物输送

与 HAMILTON-H900 配合使用的 Aerogen 雾化器 与 HAMILTON-H900 配合使用的 Aerogen 雾化器

Aerogen 雾化器。 将吸入药物输送到需要它的地方

我们提供 Aerogen 雾化解决方案，Aerogen 是世界领先的雾化器制造商和经销商，其提供高性能喷雾药物输送治疗技术。

Aerogen Solo

Aerogen Solo。 单个病人使用的雾化器

振动网技术一致的飞沫大小微粒：

  • 在模拟肺模型中观察到相比射流雾化器可改善药物输送 (Ari A, Atalay OT, Harwood R, Sheard MM, Aljamhan EA, Fink JB.Influence of nebulizer type, position, and bias flow on aerosol drug delivery in simulated pediatric and adult lung models during mechanical ventilation.Respir Care.2010;55(7):845-851.1​)
  • 无需增加流量
  • 适用于医生指定的吸入药物
  • 可由 HAMILTON-C6 和 HAMILTON-G5/S1 呼吸机内的可选内置控制器或由 Aerogen Pro-X 控制器或 Aerogen USB 控制器供电
Aerogen Pro-X 控制器

Aerogen Pro-X 控制器。 您的便携式电源

在医院内，Pro-X 控制器通过一个便携式设备为 Aerogen 技术供电。 

  • 为 Aerogen Solo 供电
  • 30 分钟和连续模式选项
  • 内部 45 分钟电池
Aerogen USB 控制器

Aerogen USB 控制器。 从任何 USB 端口供电

外形小巧的 Aerogen USB 控制器可从呼吸机上的 USB 端口为 Aerogen Solo 供电（对于美国用户，Aerogen USB 控制器应仅通过 Aerogen USB 控制器 AC/DC 接口从主电源供电。A​）。

  • 为 Aerogen Solo 供电
  • 快速且易于设置
  • 30 分钟和 6 小时模式选项
电子产品目录

有关更多信息

文件
Nebulizer positioning guidelines
英语 | 0.81 MB | ELO2020-124-TW.01
文件
Aerogen Clinical whitepaper
英语 | 3.44 MB
文件
使用说明 Aerogen Solo/Aerogen Pro HAMILTON-C6
中文 | 1.19 MB | 627134.02
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脚注

  • A. 对于美国用户，Aerogen USB 控制器应仅通过 Aerogen USB 控制器 AC/DC 适配器从主电源供电。

参考文献

  1. 1. Ari A, Atalay OT, Harwood R, Sheard MM, Aljamhan EA, Fink JB. Influence of nebulizer type, position, and bias flow on aerosol drug delivery in simulated pediatric and adult lung models during mechanical ventilation. Respir Care. 2010;55(7):845-851.

Influence of nebulizer type, position, and bias flow on aerosol drug delivery in simulated pediatric and adult lung models during mechanical ventilation.

Ari A, Atalay OT, Harwood R, Sheard MM, Aljamhan EA, Fink JB. Influence of nebulizer type, position, and bias flow on aerosol drug delivery in simulated pediatric and adult lung models during mechanical ventilation. Respir Care. 2010;55(7):845-851.



BACKGROUND

The effectiveness of aerosol drug delivery during mechanical ventilation is influenced by the patient, ventilator, and nebulizer variables. The impact of nebulizer type, position on the ventilator circuit, and bias flow on aerosol drug delivery has not been established for different age populations.

OBJECTIVE

To determine the influence of nebulizer position and bias flow with a jet nebulizer and a vibrating-mesh nebulizer on aerosol drug delivery in simulated and mechanically ventilated pediatric and adult patients.

METHOD

Albuterol sulfate (2.5 mg) was nebulized with a jet nebulizer and a vibrating-mesh nebulizer, using simulated pediatric and adult lung models. The 2 nebulizer positions were: (1) jet nebulizer placed 15 cm from the Y-piece adapter, and vibrating-mesh nebulizer attached directly to the Y-piece; and (2) jet nebulizer placed prior to the heated humidifier with 15 cm of large-bore tubing, and vibrating-mesh nebulizer positioned at an inlet to the humidifier. A ventilator with a heated humidifier and ventilator circuit was utilized in both lung models. The adult ventilator settings were V(T) 500 mL, PEEP 5 cm H2O, respiratory rate 20 breaths/min, peak inspiratory flow 60 L/min, and descending ramp flow waveform. The pediatric ventilator settings were V(T) 100 mL, PEEP 5 cm H2O, respiratory rate 20 breaths/min, inspiratory time 1 s. We tested bias flows of 2 and 5 L/min. The adult and pediatric lung models used 8-mm and 5-mm inner-diameter endotracheal tubes, respectively. Each experiment was run 3 times (n = 3). The albuterol sulfate was eluted from the filter and analyzed via spectrophotometry (276 nm).

RESULTS

Nebulizer placement prior to the humidifier increased drug delivery with both the jet nebulizer and the vibrating-mesh nebulizer, with a greater increase with the vibrating-mesh nebulizer. Higher bias flow reduced drug delivery. Drug delivery with the vibrating-mesh nebulizer was 2-4-fold greater than with the jet nebulizer at all positions (P < .05) in both lung models.

CONCLUSION

During simulated mechanical ventilation in pediatric and adult models, bias flow and nebulizer type and position impact aerosol drug delivery.