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简明扼要。 关键论文的关键成果

几个黑色箭头指向绿点

重症监护的里程碑

医学科学不会止步不前。全球范围内的研究者都在不断努力改进我们治疗重症病人的技术和方法。有时，众多文献中的一篇会使我们重新考虑，而且可能会改变研究方向。下面的论文是我们新收集文献中的第一篇转折点论文，让我们直面重点——通过拨开碎末枝节，回归关键事实和结果，以标准化、易于理解的形式呈现出来。我们希望您喜欢这篇论文，并期待收到您的反馈意见或评论。

Pes-guided-strategy_ARDS_ECMO_Cropped_16x9

Transpulmonary-pressure guided strategy in severe ARDS treated with VV-ECMO

The authors' point? A Ptp-guided ventilation strategy resulted in a greater proportion of patients with severe ARDS successfully weaned from VV-ECMO when compared to a lung-rest strategy. Read on for more!
173_TTP_Correlation-hysteresis-lung-recruitment

Correlation between the hysteresis of the PV curve and R/I ratio

The authors' point? The normalized maximum distance on a quasi-static PV curve and the recruitment-to-inflation ratio can be used at the bedside as potential indicators of lung recruitability.
174_2024_01_TTP_Depta_2022_BMC-Anesthesiol

Time constant to determine PEEP - A feasible approach?

The authors' point? Using the expiratory time constant instead of inspiratory parameters holds promise as an approach for personalized PEEP titration in patients with ARDS.
179_TTP_Bossers_2023_Initensive_Care_Med

Prehospital EtCO2 and mortality in suspected severe traumatic brain injury patients

The authors' point? Targeting EtCO2 levels of 35–45 mmHg seems reasonable during prehospital care as lower levels are associated with a significant increase in 30-day mortality.
181_TTP_Chen_2022_Partition_respiratory_mechanics

Predicting outcomes in ARDS patients – Does partitioning respiratory mechanics help?

The authors' point? Transpulmonary driving pressure is equivalent to airway driving pressure in terms of predicting outcomes. Their findings support the importance of limiting lung and airway driving pressure, while also maintaining positive end-expiratory PL in obese patients.