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 Academy

To the point. Key findings from key papers

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Milestones in critical care

Medical science never stands still. Researchers across the globe are continually striving to improve technology and the way we treat critically ill patients. Every now and then, one publication amongst the many makes us reconsider and maybe change direction. In this collection, we take these watershed papers and get straight to the point ‑ by stripping them back to the key facts and findings and presenting them in a standardized, easy‑to‑digest format. We hope you enjoy it and would love to hear your feedback or comments.

Pes-guided-strategy_ARDS_ECMO_Cropped_16x9

Transpulmonary-pressure guided strategy in severe ARDS treated with VV-ECMO

The authors' point? A Ptp-guided ventilation strategy resulted in a greater proportion of patients with severe ARDS successfully weaned from VV-ECMO when compared to a lung-rest strategy. Read on for more!
173_TTP_Correlation-hysteresis-lung-recruitment

Correlation between the hysteresis of the PV curve and R/I ratio

The authors' point? The normalized maximum distance on a quasi-static PV curve and the recruitment-to-inflation ratio can be used at the bedside as potential indicators of lung recruitability.
174_2024_01_TTP_Depta_2022_BMC-Anesthesiol

Time constant to determine PEEP - A feasible approach?

The authors' point? Using the expiratory time constant instead of inspiratory parameters holds promise as an approach for personalized PEEP titration in patients with ARDS.
179_TTP_Bossers_2023_Initensive_Care_Med

Prehospital EtCO2 and mortality in suspected severe traumatic brain injury patients

The authors' point? Targeting EtCO2 levels of 35–45 mmHg seems reasonable during prehospital care as lower levels are associated with a significant increase in 30-day mortality.
181_TTP_Chen_2022_Partition_respiratory_mechanics

Predicting outcomes in ARDS patients – Does partitioning respiratory mechanics help?

The authors' point? Transpulmonary driving pressure is equivalent to airway driving pressure in terms of predicting outcomes. Their findings support the importance of limiting lung and airway driving pressure, while also maintaining positive end-expiratory PL in obese patients.
182_TTP_Urner_2023_Crit_Care_Med

Limiting driving pressure - Does it affect mortality?

The authors' point? Limiting static or dynamic ∆P can further reduce the mortality of patients requiring mechanical ventilation.